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Updated: Jan 13, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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ピラゾフーリンの生物合成は,リースケ酵素触媒によるピリダジン中間物の非酵素環収縮を伴う

Ziyang Zheng1, Yu-Hsuan Lee2, Daan Ren2

  • 1Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.

Journal of the American Chemical Society
|October 29, 2025
PubMed
まとめ

ピラゾフーリンのような 抗菌剤や抗ウイルス剤に不可欠な ピラゾフーリンの合成のための 新しい経路を発見しました これは,酸化誘発のリング収縮を経験するユニークなピリダジン中間物質を含みます.

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