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Updated: Jan 13, 2026

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
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NMDA受容体における伝導性制御と神経ステロイド結合のメカニズム

Hyunook Kang1, Ruben Steigerwald1, Elijah Z Ullman2

  • 1W.M. Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.

Nature
|October 30, 2025
PubMed
まとめ

イオンチャネル伝導性の構造的メカニズムが明らかになった. NMDARの柔膜ポケットに結合するニューロステロイドは,チャネル曲線を制御し,伝導状態と信号強度を調節する.

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