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Updated: Jan 12, 2026

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著者訂正:頭皮に特異的なIKK2の欠損があるマウスのTNF媒介性炎症性皮膚疾患

Manolis Pasparakis1,2, Gilles Courtois3, Martin Hafner4,5

  • 1Institute for Genetics, University of Cologne, Cologne, Germany. pasparakis@embl-monterotondo.it.

Nature
|November 6, 2025
PubMed
まとめ

No abstract available in PubMed .

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The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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