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Updated: Jan 11, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
07:08

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues

Published on: July 14, 2015

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人間のプロテオームを網羅する内在的に乱れた領域の予測された分子文法

Kiersten M Ruff1, Matthew R King1, Alexander W Ying2

  • 1Department of Biomedical Engineering, Center for Biomolecular Condensates, Washington University in St. Louis, St. Louis, MO 63130, USA.

Cell
|November 13, 2025
PubMed
まとめ

本質的に無秩序な領域 (IDR) はユニークな分子文法を持っています. NARDINI+ (GIN) のリソースは,これらの文法を明らかにし,タンパク質の機能,細胞の局所化,および生物学的プロセスに関連付けています.

キーワード:
RNAポリメラーゼバイオ分子凝縮物癌について本質的に無秩序な地域分子文法サブセルロースの位置づけトランスクリプション 規制

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Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins05:08

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