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Updated: Jan 10, 2026

Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
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細菌 の 毒素 は 炎症 に 対し て の 腸 の 防御 力 を 弱める

Sonia Modilevsky1, Shai Bel1

  • 1Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.

Science (New York, N.Y.)
|November 20, 2025
PubMed
まとめ

潰瘍性大腸炎 (UC) の患者で発見された細菌は,マクロファージに毒性があり,マウスモデルでは腸炎を悪化させる. これはUCの病原化にこれらの特定の細菌が直接的な役割を果たしていることを示唆しています.

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