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Updated: Jan 6, 2026

Live Imaging of Primary Cerebral Cortex Cells Using a 2D Culture System
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Live Imaging of Primary Cerebral Cortex Cells Using a 2D Culture System

Published on: August 9, 2017

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TSCは新皮質の原始細胞バランスと上層ニューロン生成を調節する

Cristine R Casingal1,2, Naoki Nakagawa1,2,3, Keiko Yabuno-Nakagawa1,2

  • 1UNC Neuroscience Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Nature
|December 3, 2025
PubMed
まとめ

結核性硬化症複合体 (TSC) のタンパク質は,上層のニューロン生成に影響を及ぼし,先駆者のバランスを調節する. ヒトのTSCタンパク質のダウンレギュレーションは 複雑な脳機能に不可欠なニューロン数の拡大を説明するかもしれません

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Neurogenesis and Regeneration of Nervous Tissue01:15

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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