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Updated: Jan 9, 2026

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N-硫酸ヘパラン硫酸は共受容体としてリリンシグナル伝達を促進する

Lin Pan1,2, Xuehong Song3, Guowei Su4

  • 1Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, United States.

Journal of the American Chemical Society
|December 8, 2025
PubMed
まとめ

ヘパラン硫酸 (HS) はリーリンシグナル伝達のための共受容体として作用する. HSのN硫化はリーリン結合と受容体の活性化に不可欠であり,脳疾患の新たな治療標的を提供している.

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