総頸動脈分岐部における血行動態パラメータのコンピュータ支援モデリング
V P Derbilova1, R A Vinogradov1,2, Yu N Zakharov3,4
1Kuban State Medical University of Ministry of Ministry of Healthcare of the Russian Federation, 350063, Krasnodar, Russian Federation.
Background:
Computational fluid dynamics is currently widely used to study the parameters of blood flow and their alterations in pathological states and are important indicators for diagnosis of atherosclerosis.
Objective:
This study was aimed at determining risk zones for development of atherosclerosis by means of computational fluid dynamics in patients without carotid artery pathology.
Patients And Methods:
Using contrast-enhanced computed tomography, a total of 10 bifurcations of common carotid arteries were examined. The obtained findings were analyzed by means of computational fluid dynamics. The area of bifurcation was divided into segments. In each segment, we identified zones most prone to the development of atherosclerosis.
Results:
The obtained findings made it possible to draw a conclusion that in patients without pathology of carotid arteries, the zone of bifurcation is a place of potential development of atherosclerotic plaques. It was confirmed by low values of wall shear stress. Besides, our study made it possible to determine exact localization of risk zones, i. e., proximal portion of the internal carotid artery.
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関連する概念動画
Blood Flow
Three-Compartment Open Model
Steady, Laminar Flow Between Parallel Plates
Couette Flow
Typical Model Studies
Applications of Integration to Find Blood Flow
