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Tumor Immunotherapy01:27

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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CAR-T細胞療法による多発性硬化症の再定義

Yan-Ruide Li1, Yuning Chen1, Lili Yang2

  • 1Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Molecular therapy : the journal of the American Society of Gene Therapy
|December 12, 2025
PubMed
まとめ
この要約は機械生成です。

キメラ抗原受容体(CAR)-T細胞療法は、自己免疫応答を標的とすることにより、多発性硬化症(MS)の治療に有望視されています。長期的な疾患制御のためには、安全性と有効性の最適化に関するさらなる研究が必要です。

キーワード:
CAR-T細胞療法CD19標的CAR-TCRSMS自己免疫疾患自己反応性B細胞サイトカイン放出症候群多発性硬化症神経毒性

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