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Updated: Jan 8, 2026

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Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease
Published on: September 22, 2023
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パーキンソン病における消化管機能障害の開発と新たなトレンド:10年間の計量書誌学的分析
Yujia Sun1,2,3,4, Haoyu Yang1,2,3, Junfeng Zhang5
1The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Frontiers in aging neuroscience
|December 15, 2025
まとめ
消化管機能障害はパーキンソン病の主要な症状です。研究によると、その病原体、便秘などの臨床的問題、および便微生物移植などの治療法に関する出版物が増加しています。
科学分野:
- 神経学
- 消化器病学
- 計量書誌学
- Neurology; Gastroenterology; Bibliometrics
背景:
- 消化管(GI)機能障害は、パーキンソン病(PD)における一般的な非運動症状です。
- それは病気の進行と患者の生活の質に大きく影響します。
- PDにおけるGI機能障害に関する研究は、過去10年間で大幅に増加しました。
- Gastrointestinal (GI) dysfunction is a common non-motor symptom in Parkinson's disease (PD).; It significantly impacts disease progression and patient quality of life.; Research on GI dysfunction in PD has grown substantially over the last decade.
研究 の 目的:
- 消化管機能障害とパーキンソン病の研究における知識体系と進化するトレンドを体系的に分析すること。
- 主要な研究フロンティア、影響力のある出版物、および協力パターンを特定すること。
- 将来の研究と臨床実践のための洞察を提供すること。
- To systematically analyze the knowledge framework and evolving trends in GI dysfunction and PD research.; To identify key research frontiers, influential publications, and collaboration patterns.; To provide insights for future research and clinical practice.
主な方法:
- Web of Science Core Collection(WoSCC)から2015年から2025年までに発表された924本の論文の計量書誌学的分析。
- VOSviewer、CiteSpace、およびBibliometrixを使用した共起、クラスタリング、および協力ネットワーク分析。
- キーワード分析のためにPubMedデータベースを使用した検証。
- Bibliometric analysis of 924 articles published between 2015 and 2025 from the Web of Science Core Collection (WoSCC).; Co-occurrence, clustering, and collaboration network analyses using VOSviewer, CiteSpace, and Bibliometrix.; Validation using the PubMed database for keyword analysis.
主要な成果:
- 出版数は一貫して年々増加していました。中国と米国が最も多くの論文を発表した国であり、米国が最も多く引用されていました。主要な研究分野には、病原体(α-シヌクレイン、脳腸マイクロバイオーム軸)、臨床症状(嚥下困難、便秘)、および治療法(便微生物移植、プロバイオティクス)が含まれます。
- A consistent annual increase in publication output was observed.; China and the United States were the most prolific countries, with the US having the highest citations.; Key research areas include pathogenesis (α-synuclein, brain-gut-microbiome axis), clinical manifestations (dysphagia, constipation), and therapies (fecal microbiota transplantation, probiotics).
結論:
- 計量書誌学的分析により、消化管機能障害とパーキンソン病における研究分野が拡大していることが明らかになりました。
- 本研究は、病原体、臨床症状、および治療介入を強調する主要な研究フロンティアとトレンドを特定します。
- 本研究の結果は、パーキンソン病における消化管問題の将来の研究の方向性と臨床管理にガイダンスを提供します。
- Bibliometric analysis reveals a growing research landscape in GI dysfunction and PD.; The study identifies major research frontiers and trends, highlighting pathogenesis, clinical symptoms, and therapeutic interventions.; Findings offer guidance for future research directions and clinical management of GI issues in Parkinson's disease.
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