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Updated: Jan 8, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development

Published on: June 15, 2017

線維芽細胞増殖因子による増殖活性および代謝活性のシグナル伝達

Patience Salvalina Okoto¹, Zeina Alraawi¹, Thallapuranam Krishnaswamy Suresh Kumar¹

¹Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, AR 72701, USA.

Journal of cellular signaling

|December 15, 2025

Abstract:

Fibroblast growth factors are signaling molecules that play crucial roles in fundamental processes such as cell migration, proliferation, differentiation, angiogenesis, and cell survival. FGFs signal by forming a complex with tyrosine kinase FGF receptors and cofactors. It is well known that FGFs play diverse roles in different tissues and at different developmental stages due to factors such as receptors, specific FGFs, and environmental conditions such as temperature and pH. This review focuses on the actions of mitogenic and metabolic FGFs and their interactions with their receptors to trigger their designated functions.

キーワード:

細胞シグナル伝達線維芽細胞増殖因子代謝FGF 増殖FGF

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Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes

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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

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Published on: October 27, 2020

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