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サリドロシドはPPARγを介した炎症シグナル伝達経路を通じて早期MASHを軽減する

Jun Zhang1, Jintao Xuan2, Zheyun He3

  • 1Liver Disease Department of Integrative Medicine, Ningbo No.2 Hospital, Ningbo, Zhejiang, 315010, China; Department of Infectious Diseases, Affiliated Hospital of Jiaxing University/The First Hospital of Jiaxing, Jiaxing, Zhejiang, 314000, China.

Journal of ethnopharmacology
|December 15, 2025
PubMed
まとめ

ロディオラ・ロゼア由来のサリドロシドは、PPARγを活性化し炎症を阻害することでMASHを効果的に治療します。この天然化合物は肝臓の脂肪と炎症を減少させ、MASHの有望な治療法を提供します。

キーワード:
MASHNF-κBPPARγサリドロシド

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