幼少期の家族的逆境と便失禁との因果関係の検討：前向きコホート研究

Kimberley Burrows¹, Jon Heron^2,3, Davina Richardson⁴

¹Centre for Academic Child Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK kimberley.burrows@bristol.ac.uk.

BMJ paediatrics open

|December 15, 2025

まとめ

乳幼児期の家族的逆境は、小児期の昼間の便失禁および便秘のリスクを高める。早期の困難は、便秘が重要な役割を果たす便失禁と関連する。

科学分野:

小児健康
発達心理学
公衆衛生

背景:

乳幼児期の家族的逆境は、小児期の健康問題の潜在的リスク因子である。
早期の逆境と後の健康転帰を結びつける経路を理解することは、介入のために極めて重要である。

主な方法:

Avon Longitudinal Study of Parents and Childrenの10,033人の子供の前向きコホート研究。
家族的逆境指数（出生から2歳まで）、昼間の便失禁（7.5歳）、情緒的・行動的問題（4歳）、および便秘（6歳）に関するデータ収集。
交絡因子を調整した統計分析により、直接的および媒介的効果を検討した。

結論:

早期の家族的逆境は、後の小児期の便秘および昼間の便失禁の有意なリスク因子である。
便失禁または便秘の評価において、医療提供者は早期の逆境を考慮すべきである。
情緒的・行動的問題および便秘は、早期の逆境と便失禁との関連を部分的に媒介する可能性がある。

キーワード:

小児保健尿失禁疫学統計学

さらに関連する動画

05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

10.8K

13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.3K

関連する概念動画

01:28

Criteria for Causality: Bradford Hill Criteria - II

1.1K

The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts:

1.1K

01:28

Relationship with Parents: Attachment

208

Parent-child interactions lay the foundation for how we understand relationships throughout life. These interactions are not uniform across families; instead, they are shaped by a range of environmental, emotional, and behavioral factors unique to each caregiver-child dynamic. Social psychologists study these early relationships to understand how patterns formed in infancy influence social functioning and interpersonal behavior in adulthood.Attachment Theory and Early Relational ModelsJohn...

208

01:29

Psychological and Sociocultural Causes of Schizophrenia

443

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...

443

01:11

Observational Studies

10.7K

Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...

10.7K

01:23

Behavioral Genetics and Its Designs

969

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...

Pedigree Analysis