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Updated: Jan 8, 2026

Radiosynthesis of 1-2-[18F]Fluoroethyl-L-Tryptophan using a One-pot, Two-step Protocol
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Radiosynthesis of 1-2-[18F]Fluoroethyl-L-Tryptophan using a One-pot, Two-step Protocol

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アミノ酸を光化学を用いてセロトニン5-HT2Aレセプターリガンドに変換する

Joseph O S Beckett1,2, Ryan Buzdygon3, Steven Nguyen3

  • 1Department of Chemistry, University of California, Davis, California 95616, United States.

Journal of the American Chemical Society
|December 16, 2025
PubMed
まとめ

新しい光誘発サイクライゼーション法では,リング制約型トリプタミン類を合成する. これらの新型アゾチノインドールは,非幻覚性セロトニン5-HT2A受容体アゴニストとして薬剤発見の可能性を示している.

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