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Updated: Jan 8, 2026

Analyzing Multifactorial RNA-Seq Experiments with DiCoExpress
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Published on: July 29, 2022

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DiCoLo: 単一細胞データにおける局所的差次的遺伝子共発現の統合フリーかつクラスターフリー検出

Ruiqi Li1,2, Junchen Yang1,2, Pei-Chun Su3

  • 1Computational Biology & Biomedical Informatics Program, Yale University, New Haven, CT, USA.

bioRxiv : the preprint server for biology
|December 17, 2025
PubMed
まとめ

DiCoLoは、特定の細胞近傍における遺伝子協調の変化を検出し、単一細胞解析を改善します。この方法は、クラスター化やアライメントなしで、バッチ効果があっても差次的遺伝子プログラムを特定します。

キーワード:
バッチ効果クラスターフリー差次的共発現グラフ ラプラシアンモルフォゲン シグナル伝達最適輸送scRNA-seq

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