大うつ病患者における電気けいれん療法と職業機能
Maarten Pieter Bjørn-Rozing1, Merete Osler2, Martin Balslev Jørgensen3
1Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, Copenhagen K, 1014, Denmark.
Journal of affective disorders
|December 17, 2025
まとめ
電気けいれん療法(ECT)は大うつ病患者の職場復帰を当初は遅らせたが、職業機能は時間とともに改善した。この所見はECTを支持するものである。
科学分野:
- 精神医学およびメンタルヘルス
- 労働衛生
- 医療経済学
背景:
- 電気けいれん療法(ECT)は重度のうつ病の主要な治療法である。
- 患者の長期的な職業機能に対するその影響は、さらなる調査が必要である。
研究 の 目的:
- ECTを受けた大うつ病患者と受けなかった患者の労働市場の軌跡を比較する。
- ECTが雇用と社会保障給付に与える影響を評価する。
主な方法:
- デンマークにおける人口ベースのコホート研究(2000-2022)、ECT治療を受けた6672人と非ECT治療を受けた27,940人の患者を含む。
- 年齢と性別でマッチングされ、ECT施行前1年間からECT施行後3年間までの労働市場の結果を追跡した。
- シーケンス分析とCox回帰を用いて、再雇用までの時間を分析した。
主要な成果:
- ECT患者はベースライン雇用率が低かった(39.5% vs 6.9%)が、教育/結婚率は高かった。
- ECTは6ヶ月以内の職場復帰の遅延と関連していた(HR: 0.59)。
- 7〜12ヶ月(HR: 1.12)および1〜3年(HR: 1.05)で同等またはそれ以上の職場復帰が観察された。
結論:
- ECTは職業的回復の初期遅延と関連している。
- 同等またはそれ以上の長期的な職場復帰は、大うつ病に対するECTの継続使用を支持する。
- 精神科治療および患者リハビリテーションにおけるECTの役割が支持される。
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