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Updated: Jan 7, 2026

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
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Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

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長区画神経損傷における再生微小環境調節のための注入可能かつモジュール式のNO適応型デリバリーシステム

Xianzhen Dong1, Hao Zhang2, Junwei Su2

  • 1State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, China.

Advanced materials (Deerfield Beach, Fla.)
|December 19, 2025
PubMed
まとめ

本研究では、長区画神経損傷を修復するための多機能神経導管を開発した。酸化ストレスなどの障壁を克服し、神経再生を促進するために、一酸化窒素（NO）放出、先進的なヒドロゲル、および電気刺激を統合した。

キーワード:
電気刺激マイクロゲルベースヒドロゲル神経導管一酸化窒素末梢神経修復

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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