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Updated: Jan 8, 2026

Measuring the Interaction Force Between a Droplet and a Super-hydrophobic Substrate by the Optical Lever Method

Measuring the Interaction Force Between a Droplet and a Super-hydrophobic Substrate by the Optical Lever Method

Published on: June 14, 2019

原子間力顕微鏡による分子間力の測定 1：疎水性相互作用に対する溶媒の影響

Luis N Ponce-Gonzalez¹, José L Toca-Herrera¹

¹BOKU University, Institute of Biophysics, Vienna, Austria.

Microscopy research and technique

|December 19, 2025

Abstract:

Molecular forces drive phenomena such as self-assembly, aggregation, and protein folding, where hydrophobic interactions are paramount. However, the origin of the hydrophobic mechanism remains unknown. Advances in techniques like atomic force microscopy (AFM) have improved our ability to study this topic. Hydrophobic interactions are stronger and longer ranged than van der Waals (vdW) forces, potentially arising from water structuring, polarization, and entropic effects. In this primer, fluorocarbon surfaces were prepared via chemical vapor deposition (CVD) on gold to explore the impact of water:DMSO solvent binary mixtures on hydrophobic interactions. Force-distance curves measured with AFM were fitted to an extended vdW model, disclosing the influence of the medium polarity on the interactions.

キーワード:

DMSO 原子間力顕微鏡化学気相成長フッ化炭素金疎水性相互作用ファンデルワールス力

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Published on: February 27, 2015

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