中心腎細胞癌に対するエチオドール染色を伴う単回経動脈塞栓術と経皮マイクロ波焼灼術の併用療法：パイロットスタディ

This study assessed outcomes of a single-session treatment combining transarterial embolization with ethiodized oil staining and computed tomography-guided microwave ablation (TAE-MWA) for 7 patients with central renal cell carcinoma (RCC) (mean modified RENAL score 10.7 ± 0.8). Three patients had metastatic RCC and demonstrated local tumor control over a mean follow-up of 18.3 ± 11.2 months before passing away. Four patients had stage I RCC and received curative-intent treatment with durable responses for 29.8 ± 8.7 months. The mean eGFR declined six months after treatment. Although this was not statistically significant (p=0.13), the study was not powered to detect small or moderate changes in renal function. One patient developed a Grade III adverse event requiring nephrostomy. Overall, TAE-MWA appeared technically feasible for treating central RCC, demonstrating a manageable safety profile in a high-risk cohort with limited therapeutic alternatives. However, caution should be exercised when treating tumors with high nephrometry scores.