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Updated: Jan 8, 2026

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
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GPER1活性化は腎臓のプリン作動性P2Y₂受容体ナトリウム利尿経路を調節する

Supaporn Kulthinee1, Victoria L Nasci1, David M Pollock2

  • 1Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

American journal of physiology. Regulatory, integrative and comparative physiology
|December 19, 2025
PubMed
まとめ

エストラジオールはGタンパク質共役エストロゲン受容体1（GPER1）を活性化し、腎臓のナトリウム排泄を促進する。GPER1はCx30/ATP/P2Y2経路を上方制御し、雌ラットの血圧を低下させる。

キーワード:
ATPコネクシンエストロゲン高血圧プリン受容体

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