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Updated: Jan 8, 2026

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肥満修飾TyG指数を用いた胆嚢摘出術の予測精度向上：機械学習およびSHAPベースの研究

Yue Zhang1, Ruifeng Duan1, Xin Chen1

  • 1Department of Gastroenterology and Digestive Endoscopy Center, The Second Hospital of Jilin University, Changchun, People's Republic of China.

European journal of medical research
|December 19, 2025
PubMed
まとめ

TyG関連の複合指数（TyG.WHtRなど）は、胆石リスクと胆嚢摘出術の既往歴を予測します。XGB機械学習モデルは、胆嚢摘出術リスクの予測において最高の予測性能を示しました。

キーワード:
肥満度指数（TyG.BMI）胆石身長比（TyG.WHtR）中性脂肪-グルコース指数中性脂肪-グルコース指数（TyG）ウエスト腹囲（TyG.WC）

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Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
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