一次運動野への経頭蓋パルス刺激が健常成人における運動パフォーマンスに及ぼす影響：ランダム化クロスオーバーパイロットスタディ
Penny Ping Qin1, Ivan Kin-Yeung Chak1, Rebecca Lai-Di Kan1
1Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China.
Aims:
We aimed to investigate the behavioral aftereffects of a novel noninvasive brain stimulation technique-transcranial pulse stimulation (TPS)-applied over the right motor cortex (rM1) in healthy adults.
Methods:
Thirty-four healthy adults underwent a randomized, subject- and analyst- blind, crossover trial, receiving active TPS over the rM1 or control TPS over the vertex in two sessions 24 h apart. Motor performance was assessed using the Nine-Hole Peg Test (NHPT) and the Simple Reaction Time Task (SRTT) before, immediately after, and every 10 min for 40 min after each session. A linear mixed model and post hoc analyses were applied to evaluate the effects.
Results:
No significant interaction effect (stimulation condition × time) was found. The left-hand NHPT performance significantly improved from 10 min post-TPS onward in both conditions (ps ≤ 0.002).
Conclusion:
A single session of rM1-TPS does not yield significant improvements in motor dexterity compared to vertex-TPS. Future well-powered studies with a sham control condition and multiple stimulation sessions are needed to investigate the aftereffects using a combination of neurophysiological and neuroimaging approaches.
Trial Registration:
This study was registered in ClinicalTrial.gov in April 2024 (NCT06312930).
さらに関連する動画
09:52Measuring and Manipulating Functionally Specific Neural Pathways in the Human Motor System with Transcranial Magnetic Stimulation
Published on: February 23, 2020
12:13Assessing Primary Motor Cortex Excitability and Excitability Modulation by Pairing Transcranial Magnetic Stimulation with Electromyography
Published on: October 7, 2025
関連する概念動画
01:17Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
01:20Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...