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Updated: Jan 7, 2026

A Method for Targeted 16S Sequencing of Human Milk Samples

A Method for Targeted 16S Sequencing of Human Milk Samples

Published on: March 23, 2018

ヒト母乳および乳児用調製粉乳由来マイクロRNAの特性評価と乳児の健康への影響

Abdelmoneim H Ali¹, Zain Najjar², Mutamed Ayyash²

¹Department of Food Science, College of Agriculture and Veterinary Medicine, United Arab Emirates University (UAEU), Al Ain, United Arab Emirates. abdelmoneim.ali@uaeu.ac.ae.

NPJ science of food

|December 20, 2025

Abstract:

MicroRNAs (miRNAs) in human milk play a crucial role in infant development and health. These molecules are well-known to regulate gene expression and are involved in various biological processes. This review provides a comprehensive overview of the current knowledge on miRNAs in human milk and infant formulas, emphasizing their potential impact on infant health and the future directions for research in this field. Understanding the roles and functions of miRNAs for infants' health will not only disclose innovative aspects of breastfeeding, but it might pave the way for novel diagnostic and medicinal possibilities as well.

キーワード:

マイクロRNA ヒト母乳乳児用調製粉乳乳児の健康遺伝子発現乳児の発生

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MicroRNAs

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...

MicroRNAs

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...

Anatomy of the Intestines

Anatomy of the Intestines

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...