人種化された経済的隔離と妊孕性との関連:妊孕前コホート研究
Sharonda M Lovett1, Erin J Campbell2,3, Andrea S Richardson4
1Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA. slovett1@bu.edu.
Journal of urban health : bulletin of the New York Academy of Medicine
|December 20, 2025
まとめ
極端値集中指数(ICE)で測定された人種化された経済的隔離は、妊孕性の低下と関連していた。不利な地域では、妊娠率の適度な低下が見られた。
科学分野:
- 生殖疫学
- 健康の社会的決定要因
- 環境保健
背景:
- 人種化された経済的隔離は、健康格差の既知の決定要因である。
- 以前の研究では、隔離と妊娠転帰不良との関連が指摘されていた。
- 隔離と妊孕性との関連を調査した研究はなかった。
研究 の 目的:
- 居住隔離と妊孕性との関連を調査すること。
- 経済的、人種的、および人種化された経済的隔離が、周期あたりの妊娠確率に与える影響を評価すること。
主な方法:
- Pregnancy Study Onlineコホート(2013-2022)の10,438人の米国参加者の分析。
- 経済的、人種的、および人種化された経済的隔離の極端値集中指数(ICE)を居住住所を用いて計算。
- 調整済み妊孕性比(FR)を推定するために、比例確率回帰モデルを使用し、関連変数を調整した。
主要な成果:
- 経済的隔離(ICEincome)および人種化された経済的隔離(ICEincome + white/black)の五分位数の増加に伴い、妊孕性との間に単調な逆相関が観察された。
- 人種化された経済的隔離において最も不利な地域(第1五分位)に住むことは、妊孕性の適度な低下(FR = 0.79)と関連していた。
- 人種隔離(ICEwhite/black)と妊孕性との間には、関連性の証拠はほとんど見られなかった。
結論:
- 地域の人種化された経済的隔離は、妊孕性の低下と関連している。
- これらの発見は、社会的および経済的な環境要因が妊娠に与える影響を強調している。
- この関連の根底にあるメカニズムを理解するためには、さらなる研究が必要である。
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