デンマークのMSMにおけるPrEP導入に対する生物心理社会学的要因の影響
Frederik Hyllested Birn1, Henrik Vardinghus-Nielsen2
1Department of Health Science and Technology, Master of Public Health Sciences & RN, Aalborg University, Selma Lagerløfs Vej 249, 9260, Aalborg, Gistrup, Denmark. frede-birn@hotmail.com.
AIDS and behavior
|December 21, 2025
まとめ
デンマークの男性間性交渉者(MSM)における曝露前予防(PrEP)の導入率は低い。副作用への恐怖、医療機関のスティグマ、HIV感染リスクの認識がPrEP使用への意欲に大きく影響する。
科学分野:
- 公衆衛生;疫学;社会科学
背景:
- 曝露前予防(PrEP)は、特に男性間性交渉者(MSM)にとって重要なHIV予防戦略である。MSMは、世界およびデンマークにおける新規HIV症例の相当な割合を占めている。利用可能で無料アクセスが可能であるにもかかわらず、デンマークの適格MSMにおけるPrEP導入率は依然として低く、障壁に関する研究が必要とされている。
研究 の 目的:
- デンマークのMSMにおけるPrEPへの意欲と導入に影響を与える生物心理社会学的要因を調査する。適格なMSM集団内でのPrEP導入を妨げる障壁を特定する。
主な方法:
- 210人のデンマークMSMを対象に、オンライン横断的調査を実施した。PrEP使用と意欲に対する様々な要因の影響を評価するために、ロジスティック回帰モデルを用いてデータを分析した。参加者は、ソーシャルメディアおよびエイズ財団クリニックを通じて募集された。
主要な成果:
- PrEP非使用者では、使用者と比較して、医療制度におけるスティグマ(OR 2.02)および副作用への恐怖(OR 5.73)の割合が高いと報告された。非使用者の中では、副作用への高い恐怖(OR 2.00)と高い自己評価HIVリスク(OR 5.60)がPrEP使用へのより高い意欲と関連していた。調査された非使用者 の40%がPrEP適格性のデンマーク基準を満たしていた。
結論:
- 副作用への恐怖、HIV感染リスクの認識、医療機関のスティグマを含む生物心理社会学的要因が、MSMにおけるPrEP導入に大きく影響する。これらの障壁に対処することは、PrEP利用を増やし、HIV感染を減らすために不可欠である。
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