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患者由来の幾何学的統合マルチフィジックスフレームワーク：前立腺がんにおける腫瘍微小環境再プログラミングによる免疫療法的ナノ粒子送達の計算最適化

Fatemeh Mirala1, M Soltani2

  • 1Department of Mechanical Engineering, K.N. Toosi University of Technology, Tehran, Iran.

Computers in biology and medicine
|December 21, 2025
PubMed
まとめ

本研究では、腫瘍微小環境の正常化とナノキャリア送達をシミュレートすることにより、免疫チェックポイント阻害薬（ICI）に対する前立腺がんの耐性を克服するための計算モデルを開発し、抗腫瘍効果を高めました。

キーワード:
計算腫瘍学薬物送達免疫療法的ナノ粒子マルチフィジックスモデリング患者由来の幾何学的形状前立腺がん腫瘍微小環境の正常化

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