関連する実験動画

Updated: Jan 8, 2026

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
09:29

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

Published on: September 30, 2016

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レジメンチニブは、攻撃的な上皮がんの再利用のためにトランスクリプトームガイド薬を特定しました

Sonja Dorfer1, Roland Zauner1, Christina Guttmann-Gruber1

  • 1EB House Austria, Research Program for Molecular Therapy of Genodermatoses, Department of Dermatology and Allergology, University Hospital of the Paracelsus Medical University Salzburg, Austria.

The Journal of investigative dermatology
|December 21, 2025
PubMed
まとめ

MEK阻害剤であるレジメンチニブは、劣性ジストロフィック表皮水疱症（RDEB-SCC）の攻撃的な扁平上皮癌の治療に有望です。この候補薬は、前臨床研究で腫瘍の成長と浸潤を効果的に減少させました。

キーワード:
計算上の薬スクリーニング薬の再利用表皮水疱症扁平上皮癌

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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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There are several types of targeted therapies against...
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Combination Therapies and Personalized Medicine02:50

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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