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Updated: Jan 8, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

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Published on: July 5, 2021

トリソミー21における後頭蓋窩グループA上衣細胞腫

Yuta Fujimoto^1,2, Hirotaka Inoue¹, Jun-Ichiro Kuroda¹

¹Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Neuropathology : official journal of the Japanese Society of Neuropathology

|December 21, 2025

Abstract:

Brain tumors are the most common solid tumors in children. However, the risk of central nervous system tumors appears reduced in individuals with trisomy 21, particularly for tumors of nervous tissue. We present the first reported case of posterior fossa group A (PFA) ependymoma in a patient with trisomy 21. Including this case, only four cases of ependymoma in trisomy 21 have been reported. Similar to medulloblastoma, ependymoma may occur at a markedly reduced frequency in trisomy 21. Investigating the protective role of trisomy 21 in ependymoma development may provide new insights into its pathophysiology and management.

キーワード:

脳腫瘍上衣細胞腫後頭蓋窩グループA（PFA）トリソミー21

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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

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