陰茎亀頭上の前癌病変に対するネオジム：イットリウム：アルミニウム：ガーネットレーザー治療

Penile intraepithelial neoplasia (PeIN) is now the new term for premalignant penile skin lesions. It is psychologically devastating to the patient and can pose a challenge to clinicians in the diagnosis. Risk factors for the development of PeIN include phimosis, uncircumcised state, poor genital hygiene, human papillomavirus infection, and smoking. When the condition is more advanced, inguinal lymphadenectomy may be needed, which has considerable morbidity. These lesions are classified separately as Bowenoid papulosis, Bowen disease, Erythroplasia of Queyrat, and squamous cell carcinoma in situ of the penis. Initial treatment of early-stage disease is surgical and has a good prognosis.