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血管内皮細胞の老化とアテローム性動脈硬化におけるSULF1の役割：単一細胞およびバルクトランスクリプトミクスからの洞察

Meng-Ting Jiang1, Shi-Lei Wan1, Xiang-Yu Shen1

  • 1Department of Cardiology, Second Affiliated Hospital of Naval Medical University, Shanghai Cardiovascular Institute of Integrative Medicine, Shanghai, 200003, People's Republic of China.

Journal of inflammation research
|December 22, 2025
PubMed
まとめ

内皮細胞の老化はアテローム性動脈硬化を促進する。この研究では、この老化を促進する主要遺伝子としてSULF1を特定し、SULF1をアテローム性動脈硬化の潜在的な治療標的として示唆している。

キーワード:
RNAシーケンシングSULF1アテローム性動脈硬化内皮細胞老化単一細胞RNAシーケンシング

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