切除不能な胃癌の治療経路と転帰:後ろ向きコホート分析
Yonatan Lessing1,2, Tal Inbar-Weissman1,2, Ron Cohen1,2
1Division of Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, ISR.
Cureus
|December 22, 2025
まとめ
進行胃癌(AGC)の手術戦略は様々であり、細胞減少術と温熱腹腔内化学療法(CRS-HIPEC)は、選択された患者において最も長い生存期間を提供する。緩和的処置は適度な利益をもたらし、診断手術は最も低い生存率を示す。
背景:
- 進行胃癌(AGC)の管理には、多様な外科的アプローチが含まれる。; 戦略は、診断手術(DS)から緩和的処置(PP)、細胞減少術と温熱腹腔内化学療法(CRS-HIPEC)まで多岐にわたる。; これらの戦略が患者の転帰に与える影響に関する実世界データは非常に重要である。
結論:
- 切除不能なAGCの外科的戦略は多様であり、個別化が必要である。; 緩和的処置は、選択された患者において症状緩和と適度な生存期間の延長を提供する。; CRS-HIPECは、高度に選択されたコホートにおいて長期生存の可能性を示しており、さらなる調査が必要である。
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