乳房温存手術か従来の乳房切除術か？西ジャワの後ろ向きコホート研究からの転帰
Raden Yohana Azhar1, Birgitta M Dewayani2, Zuldi Erdiansyah1
1Department of Surgery of Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Purpose:
Breast-conserving surgery (BCS) followed by adjuvant radiotherapy is the standard treatment for early breast cancer in Indonesia. Our aim was to compare the outcomes of BCS with oncoplastic surgery (OPS), a less common method of breast cancer treatment in the country.
Patients And Methods:
This retrospective cohort study was conducted at Hasan Sadikin General Hospital, Bandung, West Java, Indonesia. Patients with biopsy-proven Stage I to II breast cancer who underwent either OPS or BCS between 1 July 2020 to 30 June 2023, were identified. Data were collected by reviewing patient files and electronic records.
Results:
A total of 82 patients were included in the study, with 43 (52.4%) undergoing BCS and 39 (47.6%) undergoing OPS. Age in OPS group 39.25 ± 4.9 was not significant difference compare with BCS group 39.86 ± 5.11. The mean tumor volume was higher in the OPS group (34.72 cm3) compared to the BCS group (22.35 cm3), and postoperative complications were also higher in the OPS group (7.6% vs 0%). Despite the use of frozen section analysis in the operating theatre, the frequency of positive margins was greater in the BCS group (9.3% vs 2.5%). There were no significant differences in the histologic type of tumor and immunohistochemistry between the two groups.
Conclusion:
OPS is a valid alternative approach to breast cancer treatment that can be offered to women with early stage breast cancer at complex locations owing to the reduced occurrence of positive margins and thus lowered re-excision rates.
