関連する実験動画

Updated: Jan 8, 2026

Visualization and Quantification of Endogenous Intra-Organelle Protein Interactions at ER-Mitochondria Contact Sites by Proximity Ligation Assays
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Visualization and Quantification of Endogenous Intra-Organelle Protein Interactions at ER-Mitochondria Contact Sites by Proximity Ligation Assays

Published on: October 20, 2023

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TAG-PL：ミトコンドリアプロテオームとストレス下での細胞小器官相互作用のマッピングのための普遍的な近接ラベリングプラットフォーム

Enming Miao1,2, Xuyang Yue1,2, Zhixiong Tao1,2

  • 1State Key Laboratory of Medical Proteomics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.

Journal of proteome research
|December 23, 2025
PubMed
まとめ

Tailored Antibody-Guided Proximity Labeling（TAG-PL）を開発しました。これは、ミトコンドリアタンパク質をマッピングするためのトランスフェクションフリー法であり、熱ストレス細胞におけるミトコンドリアの変化を明らかにし、ストレス顆粒-ミトコンドリア相互作用を特定します。

キーワード:
SG−ミトコンドリア相互作用抗体誘導型近接ラベリングミトコンドリアプロテオーム

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