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Updated: Jan 8, 2026

Selected Reaction Monitoring Mass Spectrometry for Absolute Protein Quantification
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Published on: August 17, 2015

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卵巣がん細胞のシスプラチン治療後のペプチドレベルの直線性評価のためのプロテオームワイドマルチポイント内部検量線

Cristina Chiva1,2, Zahra Elhamraoui1,2, Julia Morales-Sanfrutos1,2

  • 1Centre for Genomic Regulation, The Barcelona Institute of Science and Technology, Dr Aiguader 88, 08003 Barcelona, Spain.

Journal of proteome research
|December 23, 2025
PubMed
まとめ

本研究では、質量分析プロテオミクスのための新しいTMTベースの内部キャリブレーション法を導入する。このアプローチはペプチドを正確に定量し、シスプラチン治療後の卵巣がん細胞のプロテオーム変化を明らかにする。

キーワード:
プロテオミクス質量分析内部標準定量キャリブレーション曲線シスプラチン卵巣がん

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