敗血症関連多臓器不全:肺および消化管の死亡率と管理フレームワークに関する世界的展望
Yang Liu1,2, Zekun Wei1,2, Weihong Liu1,2
1Department of Emergency Center, Shandong University of Traditional Chinese Medicine Affiliated Hospital, No.42 Wenhua West Road, Jinan City, Shandong Province, 250014, China.
BMC infectious diseases
|December 24, 2025
まとめ
年間1100万人の死亡原因となる世界的な健康脅威である敗血症は、高所得国に不釣り合いに影響を与えています。この研究は、肺および消化管の敗血症による死亡率における重要な年齢および性別の格差を明らかにし、調整された介入の必要性を強調しています。
科学分野:
- グローバルヘルス;疫学;感染症
背景:
- 敗血症は世界的に死亡の主な原因であり、肺および消化管感染症が重要な要因となっています。 年間推定1100万人の死亡が敗血症に起因しており、その世界的な健康への影響を強調しています。
研究 の 目的:
- WHOの死亡率データを使用して、肺および消化管敗血症の世界的な死亡率統計を分析すること。 国や所得グループ間で、年齢および性別に特化した敗血症の死亡率の傾向を調査すること。
主な方法:
- 106か国(2017年から2021年)のWHO死亡率データベースデータの分析。 218の肺および146の消化管敗血症の死亡原因の調査。 性別に特化した年齢層別(23カテゴリ)分析の含意。
主要な成果:
- 高所得国は最も高い敗血症死亡率(人口10万人あたり1,066.76人)を示しています。 ヨーロッパ諸国はアジア諸国よりも高い死亡率を示しています。 男性は若年/中年ではより脆弱ですが、女性は高齢者ではより感受性が高くなります。 新生児の肺敗血症による死亡は男性の方が高いです。
結論:
- 敗血症による死亡率は、国の所得水準および地理的地域によって大きく異なります。 年齢と性別は、敗血症の脆弱性と死亡率の重要な決定要因です。 効果的な敗血症の予防と管理には、ターゲットを絞った年齢および性別に特化した戦略が不可欠です。
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