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Updated: Jan 8, 2026

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice

Published on: January 16, 2013

鎌状赤血球症および住血吸虫症に伴う肺高血圧症

Claudia Mickael^1,2, Jane C Kabwe^3,4, Dara Fonseca Balladares^5,6

¹Cardiovascular Pulmonary Laboratory University of Colorado Anschutz Medical Campus Aurora Colorado USA.

Pulmonary circulation

|December 24, 2025

Abstract:

Schistosomiasis and sickle cell disease (SCD) both cause pulmonary hypertension (PH). We identified a subject with sickle cell trait and hepatosplenic schistosomiasis, who on right heart catheterization had PH, but due to high cardiac output. In a pre-clinical model, we found SCD mice were protected from developing schistosomiasis-induced PH.

キーワード:

TGF-β 臨床研究同時感染マウスモデル

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Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

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Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure

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