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Updated: Jan 8, 2026

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Operant Procedures for Assessing Behavioral Flexibility in Rats
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分析基準が異なる結果を示す場合の再検査の再考
Özben Özden Işıklar1, Evin Kocatürk1, Zeynep Başoğlu1
1Department of Medical Biochemistry, Faculty of Medicine, Eskişehir Osmangazi University, Eskişehir, Turkey.
Scandinavian journal of clinical and laboratory investigation
|December 24, 2025
まとめ
臨床化学検査室における不要な再検査は一般的であり、リソースを浪費します。許容総誤差(TEa)や基準変更値(RCV)などの分析基準を適用することで、これらの再検査を減らし、効率と患者の安全性を向上させることができます。
科学分野:
- 臨床化学;検査医学;医療診断
背景:
- 緊急臨床化学検査では再検査が頻繁に行われています。;その臨床的な必要性はしばしば不確かであり、潜在的な遅延とリソースの浪費につながります。
主な方法:
- 23の分析項目にわたる18,736件の再検査結果のペアの遡及的分析が実施されました。;各ペアは、TEa_Obs、TEa_CLIA、およびRCVに基づいて、必要または不要に分類されました。;基準間の合意は、コーエンのカッパ(κ)を使用して評価され、必要または不要な再検査のターンアラウンドタイム(TAT)が比較されました。
結論:
- 分析基準の選択は、再検査の必要性の解釈と運用結果に大きく影響します。;TEa_Obs、TEa_CLIA、およびRCVを組み合わせたルール駆動型ワークフローをラボ情報システム(LIS)に実装することで、患者の安全性を損なうことなく、不要な再検査を削減し、TATを安定させ、リソース使用を最適化できます。
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