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不活化エンテロウイルス71粒子凝集安定性：動的光散乱解析と安定化剤の同定

Anna Yang1,2,3,4, Dongsheng Yang1,2,3,4, Deqin Pang1,2,3,4

  • 1Wuhan Institute of Biological Products Co., Ltd., No. 1 Huangjin Industrial Park Road, Wuhan 430207, China.

Vaccines
|December 24, 2025
PubMed
まとめ

動的光散乱（DLS）は、エンテロウイルス71（EV71）粒子の凝集を効果的に監視する。特定のpH、緩衝液、安定化剤が、環境ストレスに対するワクチンの安定性を高める。

キーワード:
動的光散乱製剤開発不活化コクサッキーウイルス71ワクチン粒子径タンパク質凝集

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