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神経変性疾患における神経画像バイオマーカー：アルツハイマー病およびレビー小体型認知症におけるMRI所見と神経病理学的所見の関連付けによる診断と治療の改善

Laura E Jonkman1, Niels Reijner1, Maud M A Bouwman1

  • 1Amsterdam UMC, location VUmc, Amsterdam, Netherlands.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 24, 2025
PubMed
まとめ

死後MRIは、生前の画像診断と神経変性疾患において正確に反映されます。この研究では、画像バイオマーカーとアルツハイマー病（AD）およびレビー小体型認知症（LBD）などの特定の病理との関連を調べ、疾患のモニタリングを支援します。

キーワード:
神経画像バイオマーカー認知症アルツハイマー病レビー小体型認知症MRI病理学神経病理学

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Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

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Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
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Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
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