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臨床症状

Carrie F Milliard1, Shana G Dodge2, Sweatha Reddy1

  • 1FTD Disorders Registry, King of Prussia, PA, USA.

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まとめ
この要約は機械生成です。

行動変異型前頭側頭型認知症（bvFTD）の診断は困難であり、ほとんどの患者が診断の遅延や誤診を経験しています。早期認識と臨床医の教育は、タイムリーなbvFTD診断と患者転帰の改善に不可欠です。

キーワード:
行動変異型前頭側頭型認知症診断の遅延誤診臨床症状早期発見

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科学分野:

  • 神経学; 神経科学; 精神医学

背景:

  • 行動変異型前頭側頭型認知症（bvFTD）は、行動、性格、実行機能の変化を呈します。bvFTDの症状は他の疾患と重複するため、誤診や治療の遅れにつながることがよくあります。この診断の遅れは、患者とその家族に大きな苦痛を与えます。

研究 の 目的:

  • 行動変異型前頭側頭型認知症（bvFTD）の患者の診断までの道のりを調査すること。bvFTD診断を得る上での課題、遅延、誤診率を特定すること。

主な方法:

  • 診断経験に関する調査を用いて、直接参加型の登録簿であるFTD疾患登録簿を利用しました。2024年5月から2025年1月にかけてbvFTDを診断されたと特定した50人の参加者からデータを収集しました。調査には、診断された個人、法的代理人、ケアパートナーが含まれました。

主要な成果:

  • 回答者の大多数（76%）がbvFTD診断までに1年以上を要し、30%は3～6年の遅延を経験しました。半数以上（52%）は、うつ病、不安症、または軽度認知障害と誤診されました。報告された苦痛を伴う症状には、気分変化（46%）、認知/判断の問題（40%）、性格変化（36%）が含まれます。

結論:

  • 診断の遅延と誤診は、行動変異型前頭側頭型認知症（bvFTD）における重大な問題です。本研究の結果は、早期のbvFTD兆候を認識するための臨床医教育の強化が必要であることを強調しています。説明のつかない行動、認知、または性格の変化がある患者にとって、診断経路の改善が不可欠です。