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Updated: Jan 7, 2026

Rapid Generation of Amyloid from Native Proteins In vitro
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UV照射により誘発される共通の皮膚アミロイド様黒色腫タンパク質凝集体

Nicholas Theodosakis, Porter B Howland, Miroslav Hejna

    bioRxiv : the preprint server for biology
    |December 25, 2025
    PubMed
    まとめ

    α-シヌクレイン凝集を伴う黒色腫タンパク質病理は、皮膚の色素沈着と老化に寄与します。紫外線はこれを悪化させますが、黒色腫細胞は凝集体を除去するためにオートファジーを使用しており、これは日焼けの重要な機能です。

    キーワード:
    黒色腫タンパク質病理α-シヌクレイン紫外線日焼けオートファジー色素沈着老化パーキンソン病

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