COVID-19がフォルクマン拘縮の発症に寄与した一例:症例報告
Tomas Maciulaitis1, Patricija Glovackaite2, Mindaugas Minderis3
1Faculty of Medicine, Institute of Clinical Medicine, Clinic of Rheumatology, Orthopedics, Traumatology and Reconstructive Surgery, Vilnius University, Vilnius, LTU.
Cureus
|December 25, 2025
まとめ
フォルクマン拘縮(VIC)は、区画症候群の重篤な合併症です。この症例は、不可逆的な筋損傷を防ぐための早期認識の重要性を強調する、COVID-19中の診断上の課題を強調しています。
科学分野:
- 整形外科学;血管外科学;感染症学
背景:
- フォルクマン拘縮(VIC)は、未治療の急性区画症候群の結果であり、不可逆的な屈曲変形を引き起こします。COVID-19パンデミックは、区画症候群のような状態の診断と管理に特有の課題をもたらします。誤診と治療の遅れは、筋壊死を含む重篤な転帰につながる可能性があります。
研究 の 目的:
- 誤診後にCOVID-19隔離中に発生したVICの症例を報告すること。COVID-19がVICの病態生理において果たす可能性のある役割を議論すること。外傷がない場合でも、区画症候群のタイムリーな認識の重要性を強調すること。
主な方法:
- 前腕屈筋群の拘縮を持つ55歳男性の症例報告。臨床症状、診断プロセス、および治療介入のレビュー。COVID-19関連の病態生理学的メカニズムの可能性についての議論。
主要な成果:
- 患者は、COVID-19隔離中に当初蜂窩織炎と誤診された症状の後、VICを発症しました。診断と介入の遅れは、筋壊死と固定された屈曲変形につながりました。外科的減圧、デブリドマン、神経剥離は、部分的な機能回復をもたらしました。
結論:
- VICを防ぐためには、外傷の有無にかかわらず、区画症候群の早期認識が不可欠です。COVID-19は、サイトカインを介した浮腫や内皮機能不全などのメカニズムを通じてVICの発症に寄与する可能性があります。パンデミック中の診断の遅れと治癒の障害は、臨床的な警戒を高める必要があります。
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