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Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

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Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
358
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

430
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
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Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

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Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
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Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

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Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
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臨床症状

Zahinoor Ismail1

  • 1Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.

Alzheimer's & dementia : the journal of the Alzheimer's Association
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PubMed
まとめ
この要約は機械生成です。

アルツハイマー病および関連認知症（ADRD）におけるせん妄は一般的であるが、検出が不十分である。新しい国際精神老年医学会（IPA）基準は、せん妄の評価を標準化し、認知症関連行動の臨床ケアと研究を改善する。

キーワード:
せん妄アルツハイマー病認知症精神運動興奮高齢者臨床症状

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科学分野:

  • 老年医学; 神経学; 精神医学

背景:

  • アルツハイマー病および関連認知症（ADRD）におけるせん妄は、著しい機能低下、入院、介護者負担につながる。アルツハイマー病（AD）の最大60％がせん妄を経験するが、しばしば検出が遅れたり、一貫性がなかったりする。現在のせん妄の症候性記述には標準化された基準がなく、効果的な測定と治療評価を妨げている。

研究 の 目的:

  • 認知症におけるせん妄（IPA）の国際精神老年医学会（IPA）基準を導入し、検証する。せん妄に対するIPAの症候群的アプローチの臨床的有用性を示す。臨床実践と研究におけるせん妄評価とコミュニケーションの標準化を改善する。

主な方法:

  • 認知症におけるせん妄（IPA）の国際精神老年医学会（IPA）基準の開発と検証。言葉による攻撃性、身体的攻撃性、過度の運動活動における苦痛な行動に基づくせん妄の定義。IPA基準の適用を例示する臨床症例の提示。

主要な成果:

  • IPA基準は、以前の症候性記述を改善する症候群的アプローチを提供する。標準化された命名法と分類法は、認知症関連行動に関する一貫したコミュニケーションを促進する。臨床症例は、IPA基準が評価、測定、意思決定に役立つことを実証する。

結論:

  • IPA基準は、認知症におけるせん妄の評価と測定のための標準化された枠組みを提供する。IPA分類法の採用は、臨床ケア、介護者コミュニケーション、研究努力を強化する。標準化された評価は、ADRDにおけるせん妄の適時かつ効果的な管理に不可欠である。