臨床症状
Rafi Haddad1,2, Rachel Ben-Hayun2,3, Andjelika Milicic4
1Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, USA.
Alzheimer's & dementia : the journal of the Alzheimer's Association
|December 25, 2025
まとめ
イスラエルアラブ人はユダヤ人よりも多くの認知症状を報告し、特に実行機能において顕著であった。身体活動の増加は認知に関する訴えの減少と関連しており、運動の重要性が強調された。
科学分野:
- 神経学; 公衆衛生学; 認知科学
背景:
- イスラエルアラブ人は、ユダヤ人と比較して脳血管疾患による死亡率が高く、血管性認知障害の有病率が高い。;本研究は、同様の脳血管リスク因子(CVRF)を持つ地域在住のアラブ人とユダヤ人の間の認知格差に対処する。
研究 の 目的:
- イスラエルにおけるアラブ人とユダヤ人の認知格差を評価する。;脳血管リスク因子、認知症状、認知評価の成績との関連を調査する。;これらの集団における身体活動が認知健康に及ぼす影響を探る。
主な方法:
- 既知の認知障害はないが、少なくとも1つのCVRFを持つ115人の参加者(アラブ人59人、ユダヤ人56人)が登録された。;参加者は認知症状質問票に記入し、モントリオール認知評価(MoCA)およびタブレットベース認知評価ツール(TabCAT)脳健康評価(BHA)バッテリーを受けた。;臨床的特徴および身体活動レベルが分析された。
主要な成果:
- アラブ人(68%)はユダヤ人(32%)と比較して認知症状を報告する割合が高かった(p=0.007)。;認知症状のある参加者は、実行機能タスク(Match)の成績が悪かった(p=0.002)。;身体活動量の増加は、報告された認知症状の減少と関連していた(p=0.01)。
結論:
- この地域スクリーニングで認知症状を報告した個人の大多数はアラブ人であった。;認知症状のある人における実行機能の低下は、潜在的に診断されていない認知障害を示唆している。;身体活動の増加は、脳の健康をサポートし、認知に関する訴えを減らすために不可欠である。
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