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Updated: Jun 22, 2026

Photo-Induced Cross-Linking of Unmodified Proteins PICUP Applied to Amyloidogenic Peptides
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スクリーニングπ拡張ルテニウム(II)錯体によるアミロイドβペプチド凝集の光誘起酸化的調節

Grace Leech1, Isabella Bayly1, Alisher Talgatov2

  • 1Department of Chemistry, Simon Fraser University, Burnaby, BC V5A-1S6, Canada.

Inorganic chemistry
|December 25, 2025
PubMed
まとめ

アミロイドβ（Aβ）凝集の制御は、アルツハイマー病（AD）治療の鍵である。新しい光活性化ルテニウム錯体、特にRu1は、光を使用して一重項酸素を生成し、Aβ分解を促進し、新しい治療アプローチを提供する。

キーワード:
光活性化ルテニウム錯体アミロイドβアルツハイマー病一重項酸素ペプチド凝集

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