HTLVとHIVの同時感染モデルの動力学:マクロファージ、潜伏細胞、および2つの遅延を伴う拡散
1School of Applied Mathematics, Shanxi University of Finance and Economics, Taiyuan, People's Republic of China.
Abstract:
Human T-lymphotropic virus (HTLV) and human immunodeficiency virus (HIV) are two retroviruses that pose a certain threat to human psychology and physiology. In this paper, we propose a diffusive HTLV and HIV coinfection model with macrophages, two delays, cell-to-cell transmission and three latently infected cells in which latent HIV infected CD4T cells, latent HIV infected macrophages, and latent HTLV infected CD4T cells are considered. Four reproduction number and four equilibria, namely, infection-free equilibrium, HIV infection equilibrium, HTLV infection equilibrium and HTLV and HIV coinfection equilibrium, are calculated and proved the global asymptotic stability of the coinfection model. Numerical simulations are executed to showcase the corresponding theoretical outcomes and uncover how macrophages and latently infected cells influence the dynamics of HTLV and HIV coinfection.
関連する概念動画
Size and Structure of Viral Genomes
Retrovirus Life Cycles


