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Updated: Jun 12, 2026

A Neonatal Mouse Spinal Cord Compression Injury Model
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小児脊髄損傷患者における指向性脳ネットワークの効果的結合の変化

Yu Wang1,2, Beining Yang1,2, Ling Wang3

  • 1Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.

CNS neuroscience & therapeutics
|December 26, 2025
PubMed
まとめ

小児脊髄損傷（SCI）は脳結合を変化させ、特にデフォルトモードネットワーク（DMN）とサリエンスネットワーク（SAN）との間で変化が生じる。後部帯状皮質（PCC）は重要な調節因子であり、SCI治療のための神経調節の潜在的な標的を示唆している。

キーワード:
小児動的因果モデリング（DCM）効果的結合（EC）独立成分分析（ICA）安静時機能的磁気共鳴画像法（rs-fMRI）脊髄損傷（SCI）

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関連する概念動画

Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...