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Long-term Depression01:05

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Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
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Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
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初期研修医におけるうつ病

Karthik Reddy1, Jaqueline Stoutin2, Zhuo Zhao3

  • 1University of Michigan Medical School, Ann Arbor, Michigan; Department of Ophthalmology, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan.

Journal of surgical education
|December 28, 2025
PubMed
まとめ

眼科インターンシップ中にうつ病率が大幅に上昇し、年間を通じて持続する。後期研修2年目開始前に、ほぼ4人に1人の研修医がうつ病を経験しており、メンタルヘルスサポートの必要性が強調される。

キーワード:
燃え尽き症候群うつ病眼科眼科研修レジデント研修研修医のメンタルヘルス

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科学分野:

  • 医学教育; メンタルヘルス; 眼科

背景:

  • インターンシップは研修医のメンタルヘルスに大きな影響を与え、新規発症うつ病は研修後も持続します。 レジデンシー中のうつ病は、キャリア満足度、離職率、医師の幸福に影響します。 眼科研修は、研修医のメンタルヘルスに影響を与える特有のストレス要因と関連しています。

研究 の 目的:

  • 眼科インターンのうつ病率を調査すること。 インターンの仕事関連要因とうつ病の関係を調べること。 インターンシップ期間中のうつ病症状の持続性を評価すること。

主な方法:

  • 前向き多施設共同コホート研究。 患者健康質問票9（PHQ-9）を用いた98人の眼科インターンの縦断的評価。 インターンシップ前および3、6、9、12ヶ月の時点でデータを収集し、仕事と睡眠時間を分析しました。

主要な成果:

  • インターンの32.7%がインターンシップ中に大うつ病を経験しました。 うつ病の症状は、インターンシップ前と比較してインターンシップ終了時に著しく増加しました。 睡眠時間の増加は、うつ病スコアの低下と有意に関連していました（p < 0.001）。

結論:

  • 眼科インターンシップ期間中、うつ病症状は増加し持続します。 後期研修2年目開始前に、ほぼ25%の研修医がうつ病を報告しました。 初期の眼科研修医のメンタルヘルスに対処するため、緊急の介入が必要です。