血小板添加液中の単一ドナー血小板における異常な黄疸性変色と容器染色：まれな観察例

Suvetha Rajendran¹, Harsha Unni¹, Mohandoss Murugesan¹

¹Transfusion Medicine, Malabar Cancer Centre, Postgraduate Institute of Oncology Sciences and Research, Thalassery, India.

|December 28, 2025

Abstract:

This report describes an unusual case of an apheresis platelet (AP) unit in platelet additive solution (PAS) exhibiting marked icteric discoloration and bag staining, despite sterile cultures and initially preserved platelet morphology. Donor evaluation revealed mild unconjugated hyperbilirubinemia, implicating donor-derived pigments as the source of discoloration. By Day 5, reduced platelet function was observed. This case underscores that icteric appearance in PAS-suspended platelets, though rare, may signal donor-related pigment transfer and warrants reevaluation of current visual inspection and acceptance for blood components.

キーワード:

アフェレーシス血小板血小板添加液血小板機能黄色の変色

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