関連する実験動画
Updated: Jan 7, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
北部ペルーにおける新型コロナウイルス感染症(COVID-19)パンデミック初期の医療従事者のうつ病と不安:多施設共同研究
Mario J Valladares-Garrido1, Carlos Culquichicon2, Milagritos Sánchez Reto3
1Escuela de Medicina Humana, Universidad Señor de Sipán, Chiclayo, Peru.
Background:
Although global evidence demonstrates a clear mental health impact of COVID-19 on healthcare workers, data from Latin American settings, particularly during the first pandemic wave and within social security hospital systems, remain limited and heterogeneous. The objective was to determine the prevalence and factors associated with depression and anxiety in health human resources of three hospitals of the Social Security of Piura and Lambayeque, during the first pandemic wave of COVID-19.
Methods:
Cross-sectional analytical study in which anxiety and depression, and their association with resilience, insomnia, physical activity, eating disorder, tobacco and alcohol consumption, Burnout Syndrome and physical, psychosocial, occupational and personal health variables were evaluated. Multivariate analyses were used to estimate prevalence ratios (PR) and generalized linear models (GLM) to identify association between variables.
Results:
Of 182 health care workers, the prevalence of depression and anxiety was 42.9% and 50.6%, respectively. The factors associated with depression were being diabetic (PR: 1.41), mistreatment (PR: 1.35), moderate concern about working in a COVID environment (PR: 1.23), much/extreme concern about working in a COVID environment (PR: 1.23), much/extreme concern about being marginalized by the surrounding environment (PR: 2.00), insomnia (PR: 1.62) and burnout syndrome (PR: 1.42). The factors associated with anxiety were moderate (PR: 1.92) and very/extreme worry (PR: 2.25) about working in a COVID-19 environment, moderate (PR: 1.26) and very/extreme (PR: 1.85) and worry about being marginalized by the neighborhood environment.
Conclusions:
There is an urgent need for action to address the mental health of these professionals, who have played a critical role in pandemic response and care.
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